IUBMB Enzyme Nomenclature


Accepted name: lipopolysaccharide 3-α-galactosyltransferase

Reaction: UDP-α-D-galactose + lipopolysaccharide = UDP + 3-α-D-galactosyl-[lipopolysaccharide glucose]

Other name(s): UDP-galactose:lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:polysaccharide galactosyltransferase; uridine diphosphate galactose:lipopolysaccharide α-3-galactosyltransferase; uridine diphosphogalactose-lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:lipopolysaccharide 3-α-D-galactosyltransferase

Systematic name: UDP-α-D-galactose:lipopolysaccharide 3-α-D-galactosyltransferase

Comments: Transfers D-galactosyl residues to D-glucose in the partially completed core of lipopolysaccharide [cf. EC (lipopolysaccharide N-acetylglucosaminyltransferase), EC (lipopolysaccharide glucosyltransferase I) and EC (lipopolysaccharide glucosyltransferase II)].

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9073-98-7


1. Endo, A. and Rothfield, L. Studies of a phospholipid-requiring bacterial enzyme. I. Purification and properties of uridine diphosphate galactose: lipopolysaccharide α-3-galactosyl transferase. Biochemistry 8 (1969) 3500-3507. [PMID: 4898284]

2. Wollin, R., Creeger, E.S., Rothfield, L.I., Stocker, B.A.D. and Lindberg, A.A. Salmonella typhimurium mutants defective in UDP-D-galactose:lipopolysaccharide α-1,6-D-galactosyltransferase. Structural, immunochemical, and enzymologic studies of rfaB mutants. J. Biol. Chem. 258 (1983) 3769-3774. [PMID: 6403519]

[EC created 1972, modified 2002]

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