Reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide
Other name(s): UDP-glucose:lipopolysaccharide glucosyltransferase I; lipopolysaccharide glucosyltransferase; uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I; uridine diphosphoglucose-lipopolysaccharide glucosyltransferase
Systematic name: UDP-glucose:lipopolysaccharide glucosyltransferase
Comments: Transfers glucosyl residues to the backbone portion of lipopolysaccharide [cf. EC 2.4.1.44 (lipopolysaccharide 3-α-galactosyltransferase, EC 2.4.1.56 (lipopolysaccharide N-acetylglucosaminyltransferase) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)].
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9074-00-4
References:
1. Müller, E., Hinckley, A. and Rothfield, L. Studies of phospholipid-requiring bacterial enzymes. 3. Purification and properties of uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I. J. Biol. Chem. 247 (1972) 2614-2622. [PMID: 4553445]
2. Rothfield, L., Osborn, M.J. and Horecker, B.L. Biosynthesis of bacterial lipopolysaccharide. II. Incorporation of glucose and galactose catalyzed by particulate and soluble enzymes in salmonella. J. Biol. Chem. 239 (1964) 2788-2795.