IUBMB Enzyme Nomenclature


Accepted name: histidine transaminase

Reaction: L-histidine + 2-oxoglutarate = (imidazol-5-yl)pyruvate + L-glutamate

For diagram click here (mechanism).

Other name(s): histidine aminotransferase; histidine-2-oxoglutarate aminotransferase

Systematic name: L-histidine:2-oxoglutarate aminotransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37277-92-2


1. Coote, J.G. and Hassal, H. The role of imidazol-5-yl-lactate-nicotinamide-adenine dinucleotide phosphate oxidoreductase and histidine-2-oxoglutarate aminotransferase in the degradation of imidazol-5-yl-lactate by Pseudomonas acidovorans. Biochem. J. 111 (1969) 237-239. [PMID: 4303364]

2. Wickremasinghe, R., Hedegaard, J. and Roche, J. Dégradation de la L-histidine chez Escherichia coli B: formation de l'acide imidazolepyruvique par une histidine-transaminase. C.R. Soc. Biol. 161 (1967) 1891-1896.

[EC created 1972]

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