IUBMB Enzyme Nomenclature

EC 2.6.1.75

Accepted name: cysteine-conjugate transaminase

Reaction: S-(4-bromophenyl)-L-cysteine + 2-oxoglutarate = S-3-[(4-bromophenyl)sulfanyl]-2-oxopropanoate + L-glutamate

For diagram click here (mechanism).

Other name(s): cysteine conjugate aminotransferase; cysteine-conjugate α-ketoglutarate transaminase (CAT-1)

Systematic name: S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase

Comments: A number of cysteine conjugates can also act.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 117698-05-2

References:

1. Tomisawa, H., Ichimoto, N., Takanohashi, Y., Ichihara, S., Fukazawa, H. and Tateishi, M. Purification and characterization of cysteine conjugate transaminases from rat liver. Xenobiotica 18 (1988) 1015-1028. [PMID: 2852419]

[EC 2.6.1.75 created 1992]


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