IUBMB Enzyme Nomenclature

EC 2.7.7.107

Accepted name: (2-aminoethyl)phosphonate cytidylyltransferase

Reaction: CTP + (2-aminoethyl)phosphonate = diphosphate + CMP-(2-aminoethyl)phosphonate

Other name(s): pntC (gene name)

Systematic name: CTP:(2-aminoethyl)phosphonate cytidylyltransferase

Comments: This bacterial enzyme activates (2-aminoethyl)phosphonate for incorporation into cell wall phosphonoglycans and phosphonolipids, much like EC 2.7.7.15, choline-phosphate cytidylyltransferase, activates phosphocholine for the same purpose.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Rice, K., Batul, K., Whiteside, J., Kelso, J., Papinski, M., Schmidt, E., Pratasouskaya, A., Wang, D., Sullivan, R., Bartlett, C., Weadge, J.T., Van der Kamp, M.W., Moreno-Hagelsieb, G., Suits, M.D. and Horsman, G.P. The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis. Nat. Commun. 10 (2019) 3698. [PMID: 31420548]

[EC 2.7.7.107 created 2021]


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