IUBMB Enzyme Nomenclature


Accepted name: phosphatidate cytidylyltransferase

Reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol

Other name(s): CDP diglyceride pyrophosphorylase; CDP-diacylglycerol synthase; CDP-diacylglyceride synthetase; cytidine diphosphoglyceride pyrophosphorylase; phosphatidate cytidyltransferase; phosphatidic acid cytidylyltransferase; CTP:1,2-diacylglycerophosphate-cytidyl transferase; CTP-diacylglycerol synthetase; DAG synthetase; CDP-DG

Systematic name: CTP:phosphatidate cytidylyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9067-83-8


1. Carter, J.R. and Kennedy, E.P. Enzymatic synthesis of cytidine diphosphate diglyceride. J. Lipid Res. 7 (1966) 678-683. [PMID: 4291255]

2. McCaman, R.E. and Finnerty, W.R. Biosynthesis of cytidine diphosphate-diglyceride by a particulate fraction from Micrococcus cerificans. J. Biol. Chem. 243 (1968) 5074-5080. [PMID: 5679981]

3. Petzold, G.L. and Agranoff, B.W. The biosynthesis of cytidine diphosphate diglyceride by embryonic chick brain. J. Biol. Chem. 242 (1967) 1187-1191. [PMID: 6067194]

[EC created 1972]

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