Reaction: ATP + streptomycin = diphosphate + 3"-adenylylstreptomycin
Other names: streptomycin adenylate synthetase; streptomycin adenyltransferase; streptomycin adenylylase; streptomycin adenylyltransferase; streptomycin-spectinomycin adenylyltransferase; AAD (3"); aminoglycoside 3"-adenylyltransferase
Systematic name: ATP:streptomycin 3"-adenylyltransferase
Comments: Also acts on spectinomycin.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 52660-23-8
References:
1. Hartwood, J.H. and Smith, D.H. Resistance factor-mediated streptomycin resistance. J. Bacteriol. 97 (1969) 1262-1271. [PMID: 4887506]