IUBMB Enzyme Nomenclature

EC 2.7.7.52

Accepted name: RNA uridylyltransferase

Reaction: UTP + RNAn = diphosphate + RNAn+1

Other name(s): terminal uridylyltransferase; TUT

Systematic name: UTP:RNA uridylyltransferase

Comments: The enzyme requires an oligoribonucleotide or polyribonucleotide with a free terminal 3'-OH as a primer.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 78519-53-6

References:

1. Zabel, P., Dorssers, L., Wernars, K. and van Kammen, A. Terminal uridylyl transferase of Vigna unguiculata: purification and characterization of an enzyme catalyzing the addition of a single UMP residue to the 3'-end of an RNA primer. Nucleic Acids Res. 9 (1981) 2433-2453. [PMID: 6269049]

[EC 2.7.7.52 created 1983]


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