IUBMB Enzyme Nomenclature


Accepted name: CDP-diacylglycerol—serine O-phosphatidyltransferase

Reaction: CDP-diacylglycerol + L-serine = CMP + (3-sn-phosphatidyl)-L-serine

Other name(s): phosphatidylserine synthase; CDP-diglyceride-serine O-phosphatidyltransferase; PS synthase; cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDP-diglyceride):L-serine O-phosphatidyltransferase; phosphatidylserine synthetase; CDP-diacylglycerol-L-serine O-phosphatidyltransferase; cytidine diphosphoglyceride-serine O-phosphatidyltransferase; CDP-diglyceride-L-serine phosphatidyltransferase; CDP-diglyceride:serine phosphatidyltransferase; cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase; CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase

Systematic name: CDP-diacylglycerol:L-serine 3-sn-phosphatidyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9068-48-8


1. Larson, T.J. and Dowhan, W. Ribosomal-associated phosphatidylserine synthetase from Escherichia coli: purification by substrate-specific elution from phosphocellulose using cytidine 5'-diphospho-1,2-diacyl-sn-glycerol. Biochemistry 15 (1976) 5212-5218. [PMID: 187212]

2. Raetz, C.R.H. and Kennedy, E.P. Partial purification and properties of phosphatidylserine synthetase from Escherichia coli. J. Biol. Chem. 249 (1974) 5038-5045. [PMID: 4604873]

[EC created 1972, modified 1976]

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