IUBMB Enzyme Nomenclature


Accepted name: poly(ethylene terephthalate) hydrolase

Reaction: (ethylene terephthalate)n + H2O = (ethylene terephthalate)n-1 + ethylene terephthalate

Glossary: poly(ethylene terephthalate) = PET
ethylene terephthalate = 4-[(2-hydroxyethoxy)carbonyl]benzoate

Other name(s): PETase; PET hydrolase

Systematic name: poly(ethylene terephthalate) hydrolase

Comments: The enzyme, isolated from the bacterium Ideonella sakaiensis, also produces small amounts of terephthalate (cf. EC, mono(ethylene terephthalate) hydrolase). The reaction takes place on PET-film placed in solution.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number:


1. Yoshida, S., Hiraga, K., Takehana, T., Taniguchi, I., Yamaji, H., Maeda, Y., Toyohara, K., Miyamoto, K., Kimura, Y. and Oda, K. A bacterium that degrades and assimilates poly(ethylene terephthalate). Science 351 (2016) 1196-1199. [PMID: 26965627]

[EC created 2016]

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