IUBMB Enzyme Nomenclature


Accepted name: mono(ethylene terephthalate) hydrolase

Reaction: ethylene terephthalate + H2O = terephthalate + ethylene glycol

Glossary: ethylene terephthalate = mono(ethylene terephthalate) = MHET = 4-[(2-hydroxyethoxy)carbonyl]benzoate

Other name(s): MHET hydrolase; MHETase

Systematic name: ethylene terephthalate acylhydrolase

Comments: The enzyme, isolated from the bacterium Ideonella sakaiensis, has no activity with poly(ethylene terephthalate) PET (cf. EC, poly(ethylene terephthalate) hydrolase).

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number:


1. Yoshida, S., Hiraga, K., Takehana, T., Taniguchi, I., Yamaji, H., Maeda, Y., Toyohara, K., Miyamoto, K., Kimura, Y. and Oda, K. A bacterium that degrades and assimilates poly(ethylene terephthalate). Science 351 (2016) 1196-1199. [PMID: 26965627]

[EC created 2016]

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