IUBMB Enzyme Nomenclature

EC 3.1.3.49

Accepted name: [pyruvate kinase]-phosphatase

Reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate

Other name(s): pyruvate kinase phosphatase

Systematic name: [ATP:pyruvate 2-O-phosphotransferase]-phosphate phosphohydrolase

Comments: Simultaneously dephosphorylates and activates EC 2.7.1.40 pyruvate kinase, that has been inactivated by protein kinase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 79986-25-7

References:

1. Jett, M.-F., Hue, L. and Hers, H.-G. Pyruvate kinase phosphatase. FEBS Lett. 132 (1981) 183-186. [PMID: 6271587]

[EC 3.1.3.49 created 1984]


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