EC 3.5.1.58

Reaction: N-benzyloxycarbonylglycine + H₂O = benzyl alcohol + CO₂ + glycine

Other name(s): benzyloxycarbonylglycine hydrolase; N^α-carbobenzoxyamino acid amidohydrolase; N^α-benzyloxycarbonyl amino acid urethane hydrolase; N^α-benzyloxycarbonyl amino acid urethane hydrolase I

Systematic name: N-benzyloxycarbonylglycine urethanehydrolase

Comments: Also acts, more slowly, on N-benzyloxycarbonylalanine, but not on the corresponding derivatives of other amino acids or on N-benzyloxycarbonylpeptides. Requires Co²⁺ or Zn²⁺. cf. EC 3.5.1.64 N^α-benzyloxycarbonylleucine hydrolase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 91930-69-7

References:

1. Murao, S., Matsumura, E. and Kawano, T. Isolation and characterization of a novel enzyme, N^α-benzyloxycarbonyl amino acid urethane hydrolase, from Streptococcus faecalis R ATCC 8043. Agric. Biol. Chem. 49 (1985) 967-972.