EC 3.5.1.64

Reaction: N^α-benzyloxycarbonyl-L-leucine + H₂O = benzyl alcohol + CO₂ + L-leucine

Other name(s): benzyloxycarbonylleucine hydrolase; N^α-benzyloxycarbonyl amino acid urethane hydrolase IV

Systematic name: N^α-benzyloxycarbonyl-L-leucine urethanehydrolase

Comments: Also acts on N^α-t-butoxycarbonyl-L-leucine, and, more slowly, on the corresponding derivatives of L-aspartate, L-methionine, L-glutamate and L-alanine. cf. EC 3.5.1.58 N-benzyloxycarbonylglycine hydrolase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 100630-47-5

References:

1. Matsumura, E., Shin, T., Murao, S., Sakaguchi, M. and Kawano, T. A novel enzyme, N^α-benzyloxycarbonyl amino acid urethane hydrolase IV. Agric. Biol. Chem. 49 (1985) 3643-3645.