IUBMB Enzyme Nomenclature


Accepted name: glycosphingolipid deacylase

Reaction: Hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives

Other name(s): glycosphingolipid ceramide deacylase

Systematic name: glycosphingolipid amidohydrolase

Comments: Does not act on sphingolipids such as ceramide. Not identical with EC ceramidase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 122544-53-0


1. Hirabayashi, Y., Kimura, M., Matsumoto, M., Yamamoto, K., Kadowaki, S. and Tochikura, T. A novel glycosphingolipid hydrolyzing enzyme, glycosphingolipid ceramide deacylase, which cleaves the linkage between the fatty acid and sphingosine base in glycosphingolipids. J. Biochem. (Tokyo) 103 (1988) 1-4. [PMID: 3360750]

[EC created 1990]

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