IUBMB Enzyme Nomenclature


Accepted name: indolepyruvate decarboxylase

Reaction: 3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO2

Glossary: thiamine diphosphate

Other name(s): indol-3-yl-pyruvate carboxy-lyase

Systematic name: 3-(indol-3-yl)pyruvate carboxy-lyase [2-(indol-3-yl)acetaldehyde-forming]

Comments: Thiamine diphosphate- and Mg2+-dependent. More specific than EC pyruvate decarboxylase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9074-92-4, 183213-32-3


1. Koga, J. Structure and function of indolepyruvate decarboxylase, a key enzyme in indole-3-pyruvic acid biosynthesis. Biochim. Biophys. Acta 1249 (1995) 1-13. [PMID: 7766676]

[EC created 1999]

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