IUBMB Enzyme Nomenclature

EC 4.1.2.49

Accepted name: L-allo-threonine aldolase

Reaction: L-allo-threonine = glycine + acetaldehyde

Systematic name: L-allo-threonine acetaldehyde-lyase (glycine-forming)

Comments: Requires pyridoxal phosphate. This enzyme, characterized from the bacterium Aeromonas jandaei, is specific for L-allo-threonine and can not act on either L-threonine or L-serine. Different from EC 4.1.2.5, L-threonine aldolase, and EC 4.1.2.48, low-specificity L-threonine aldolase. A previously listed enzyme with this name, EC 4.1.2.6, was deleted in 1971 after it was found to be identical to EC 2.1.2.1, glycine hydroxymethyltransferase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:

References:

1. Kataoka, M., Wada, M., Nishi, K., Yamada, H. and Shimizu, S. Purification and characterization of L-allo-threonine aldolase from Aeromonas jandaei DK-39. FEMS Microbiol. Lett. 151 (1997) 245-248. [PMID: 9228760]

[EC 4.1.2.49 created 2011]


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