IUBMB Enzyme Nomenclature

EC 4.1.2.5

Accepted name: L-threonine aldolase

Reaction: L-threonine = glycine + acetaldehyde

Other name(s): L-threonine acetaldehyde-lyase

Systematic name: L-threonine acetaldehyde-lyase (glycine-forming)

Comments: A pyridoxal-phosphate protein. This enzyme is specific for L-threonine and can not utilize L-allo-threonine. Different from EC 4.1.2.49, L-allo-threonine aldolase, and EC 4.1.2.48, low-specificity L-threonine aldolase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 62213-23-4

References:

1. Dainty, R.H. Purification and properties of threonine aldolase from Clostridium pasteurianum. Biochem. J. 117 (1970) 585-592. [PMID: 5419751]

2. Karasek, M.A. and Greenberg, D.M. Studies on the properties of threonine aldolases. J. Biol. Chem. 227 (1957) 191-205. [PMID: 13449064]

[EC 4.1.2.5 created 1961, deleted 1972, reinstated 1976, modified 2011]


Return to EC 4.1.2 home page
Return to EC 4.3 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page