IUBMB Enzyme Nomenclature


Accepted name: (R)-citramalyl-CoA lyase

Reaction: (3R)-citramalyl-CoA = acetyl-CoA + pyruvate

Other name(s): Ccl

Systematic name: (3R)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming)

Comments: Requires Mn2+ ions for activity. The enzyme, purified from the bacterium Chloroflexus aurantiacus, has no activity with (3S)-citramalyl-CoA (cf. EC, (S)-citramalyl-CoA lyase).

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Friedmann, S., Alber, B.E. and Fuchs, G. Properties of R-citramalyl-coenzyme A lyase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus. J. Bacteriol. 189 (2007) 2906-2914. [PMID: 17259315]

[EC created 2014]

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