IUBMB Enzyme Nomenclature


Accepted name: anhydrosialidase

Reaction: Elimination of α-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-α-N-acetylneuraminate

For diagram click here.

Other name(s): anhydroneuraminidase; sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing); sialidase L

Systematic name: glycoconjugate sialyl-lyase (2,7-cyclizing)

Comments: Also acts on N-glycolylneuraminate glycosides. cf. EC (exo-α-sialidase) and EC (endo-α-sialidase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 157857-11-9


1. Li, Y.-T., Nakagawa, H., Ross, S.A., Hansson, G.C. and Li, S.C. A novel sialidase which releases 2,7-anhydro-α-N-acetylneuraminic acid from sialoglycoconjugates. J. Biol. Chem. 265 (1990) 21629-21633. [PMID: 91072361]

[EC created 1992 as EC, transferred 2003 to EC]

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