EC 4.2.3.172

Reaction: (2E,6E)-farnesyl diphosphate + H₂O = 10-epi-juneol + diphosphate

For diagram of reaction click here

Glossary: 10-epi-juneol = 10α-eudesm-4(14)-en-6α-ol

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 10-epi-juneol-forming)

Comments: Isolated from the plant Inula hupehensis. The enzyme also gives gives τ-cadinol and traces of other terpenoids, see EC 4.2.3.173, τ-cadinol synthase.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Gou, J.B., Li, Z.Q., Li, C.F., Chen, F.F., Lv, S.Y. and Zhang, Y.S. Molecular cloning and functional analysis of a 10-epi-junenol synthase from Inula hupehensis. Plant Physiol. Biochem. 106 (2016) 288-294. [PMID: 27231873]