IUBMB Enzyme Nomenclature


Accepted name: tuliposide B-converting enzyme

Reaction: 6-tuliposide B = tulipalin B + D-glucose

Glossary: 6-tuliposide B = 6-O-[(3S)-3,4-dihydroxy-2-methylenebutanoyl]-D-glucose
tulipalin B = (4S)-4-hydroxy-3-methylideneoxolan-2-one

Systematic name: 6-tuliposide B D-glucose-lyase (tulipalin B-forming)

Comments: The enzyme, characterized from pollen of the plant Tulipa gesneriana (tulip), catalyses the intramolecular transesterification of 6-tuliposide B to form the antibiotic aglycon tulipalin B as a sole product. It does not catalyse the hydrolysis of 6-tuliposide B to form a hydroxy acid. The enzyme has marginal activity with 6-tuliposide A. cf. EC, tuliposide A-converting enzyme.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Nomura, T., Murase, T., Ogita, S. and Kato, Y. Molecular identification of tuliposide B-converting enzyme: a lactone-forming carboxylesterase from the pollen of tulip. Plant J. 83 (2015) 252-262. [PMID: 25997073]

[EC created 2016]

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