Reaction: D-arabinose = D-ribulose
For diagram of reaction click here.
Other name(s): D-arabinose(L-fucose) isomerase; L-fucose isomerase; D-arabinose ketol-isomerase; arabinose isomerase (misleading)
Systematic name: D-arabinose aldose-ketose-isomerase
Comments: Requires a divalent metal ion (the enzyme from the bacterium Escherichia coli prefers Mn2+). The enzyme binds the closed form of the sugar and catalyses ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene-diol mechanism . The enzyme catalyses the aldose-ketose isomerization of several sugars. Most enzymes also catalyse the reaction of EC 220.127.116.11, L-fucose isomerase . The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose . cf. EC 18.104.22.168, L-arabinose isomerase.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 9023-81-8
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