IUBMB Enzyme Nomenclature


Accepted name: ribose-5-phosphate isomerase

Reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate

For diagram of reaction click here, alternative click here.

Other name(s): phosphopentosisomerase; phosphoriboisomerase; ribose phosphate isomerase; 5-phosphoribose isomerase; D-ribose 5-phosphate isomerase; D-ribose-5-phosphate ketol-isomerase

Systematic name: D-ribose-5-phosphate aldose-ketose-isomerase

Comments: Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9023-83-0


1. Dickens, F. and Williamson, D.H. Pentose phosphate isomerase and epimerase from animal tissues. Biochem. J. 64 (1956) 567-578.

2. Horecker, B.L., Smyrniotis, P.Z. and Seegmiller, J.E. The enzymatic conversion of 6-phosphogluconate to ribulose-5-phosphate and ribose-5-phosphate. J. Biol. Chem. 193 (1951) 383-396.

3. Hurwitz, J., Weissbach, A., Horecker, B.L. and Smyrniotis, P.Z. Spinach phosphoribulokinase. J. Biol. Chem. 218 (1956) 769-783.

[EC created 1961]

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