IUBMB Enzyme Nomenclature


Accepted name: 23S rRNA pseudouridine2457 synthase

Reaction: 23S rRNA uridine2457 = 23S rRNA pseudouridine2457

For diagram of mechanism click here.

Other name(s): RluE; YmfC

Systematic name: 23S rRNA-uridine2457 uracil mutase

Comments: The enzyme modifies uridine2457 in a stem of 23S RNA in Escherichia coli.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:


1. Del Campo, M., Kaya, Y. and Ofengand, J. Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli. RNA 7 (2001) 1603-1615. [PMID: 11720289]

2. Pan, H., Ho, J.D., Stroud, R.M. and Finer-Moore, J. The crystal structure of E. coli rRNA pseudouridine synthase RluE. J. Mol. Biol. 367 (2007) 1459-1470. [PMID: 17320904]

[EC created 2011]

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