IUBMB Enzyme Nomenclature


Accepted name: 23S rRNA pseudouridine2605 synthase

Reaction: 23S rRNA uridine2605 = 23S rRNA pseudouridine2605

For diagram of mechanism click here.

Other name(s): RluB; YciL

Systematic name: 23S rRNA-uridine2605 uracil mutase

Comments: Pseudouridine synthase RluB converts uridine2605 of 23S rRNA to pseudouridine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:


1. Del Campo, M., Kaya, Y. and Ofengand, J. Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli. RNA 7 (2001) 1603-1615. [PMID: 11720289]

2. Jiang, M., Sullivan, S.M., Walker, A.K., Strahler, J.R., Andrews, P.C. and Maddock, J.R. Identification of novel Escherichia coli ribosome-associated proteins using isobaric tags and multidimensional protein identification techniques. J. Bacteriol. 189 (2007) 3434-3444. [PMID: 17337586]

[EC created 2011]

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