IUBMB Enzyme Nomenclature


Accepted name: ABC-type D-xylose/L-arabinose transporter

Reaction: (1) ATP + H2O + D-xylose-[xylose-binding protein][side 1] = ADP + phosphate + D-xylose[side 2] + [xylose-binding protein][side 1]
(2) ATP + H2O + L-arabinose-[arabinose-binding protein][side 1] = ADP + phosphate + L-arabinose[side 2] + [arabinose-binding protein][side 1]

Systematic name: ATP phosphohydrolase (ABC-type, D-xylose/L-arabinose-importing)

Comments: ATP-binding cassette (ABC) type transporter with a 10-transmembrane-spanning (TMD) subunit and a single nucleotide binding domain. The enzyme from the archaeon Sulfolobus acidocaldarius interacts with an extracytoplasmic sugar-binding protein and mediates the uptake of of D-xylose and L-arabinose (cf. EC, ABC-type D-xylose transporter and EC, ABC-type L-arabinose transporter).

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Wagner, M., Shen, L., Albersmeier, A., van der Kolk, N., Kim, S., Cha, J., Braesen, C., Kalinowski, J., Siebers, B. and Albers, S.-V. Sulfolobus acidocaldarius transports pentoses via a carbohydrate uptake transporter 2 (CUT2)-type ABC transporter and metabolizes them through the aldolase-independent Weimberg pathway. Appl. Environ. Microbiol. 84 (2018) e01273-17. [PMID: 29150511]

[EC created 2019]

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