Possible Mechanism of

EC glycine reductase R = H
EC sarcosine reductase R3 = H2,Me
EC betaine reductase R = Me

© IUBMB 2003

The ammonia or methylamine generated may form a Schiff base with the pyruvoyl group shown either before or after cleavage of the C-N bond [See related mechanism for EC, D-proline reductase(dithiol)].

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EC glycine reductase
EC sarcosine reductase
EC betaine reductase