New enzymes (February 2001, approved April 2001)An asterisk before 'EC' indicates that this is an amendment to an existing enzyme rather than a new enzyme entry.
New enzymes (May 2001, approved August 2001)
New peptidases (May 2001, approved August 2001)
New enzymes (August 2001, approved November 2001)
New enzymes (November 2001, approved January 2002)
Minor changes
EC 1.1.1.242 now EC 1.3.1.69
*EC 1.1.1.247 codeinone reductase (NADPH)
*EC 1.1.1.248 salutaridine reductase (NADPH)
*EC 1.1.1.260 sulcatone reductase
EC 1.1.1.266 dTDP-4-dehydro-6-deoxyglucose reductase
EC 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase
EC 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase
EC 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase
*EC 1.1.3.8 L-gulonolactone oxidase
*EC 1.1.3.28 nucleoside oxidase
EC 1.1.3.39 nucleoside oxidase (H2O2-forming)
EC 1.1.3.40 D-mannitol oxidase
EC 1.3.1.69 zeatin reductase
EC 1.3.1.70 δ14-sterol reductase
EC 1.3.1.71 δ24(241)-sterol reductase
EC 1.3.1.72 δ24-sterol reductase
*EC 1.4.1.13 glutamate synthase (NADPH)
EC 1.5.99.12 cytokinin dehydrogenase
*EC 1.7.2.1 nitrite reductase (cytochrome; NO-forming)
EC 1.7.2.2 nitrite reductase (cytochrome; ammonia-forming)
EC 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)
EC 1.12.99.5 Deleted, identical to EC 1.13.11.47
*EC 1.13.11.46 4-hydroxymandelate synthase
EC 1.13.11.47 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
EC 1.13.11.48 3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase
EC 1.13.11.49 chlorite O2-lyase
EC 1.13.12.10 Deleted, reaction covered by EC 1.14.13.59
*EC 1.13.12.12 apo-β-carotenoid-14',13'-dioxygenase
EC 1.13.99.5 Transferred now EC 1.13.11.47
EC 1.14.11.19 leucocyanidin oxygenase
EC 1.14.12.18 biphenyl 2,3-dioxygenase
*EC 1.14.13.41 tyrosine N-monooxygenase
*EC 1.14.13.59 L-lysine 6-monooxygenase (NADPH)
EC 1.14.13.69 alkene monooxygenase
EC 1.14.13.70 sterol 14-demethylase
EC 1.14.13.71 N-methylcoclaurine 3'-monooxygenase
EC 1.14.15.7 choline monooxygenase
EC 1.14.99.36 β-carotene 15,15'-monooxygenase
*EC 1.15. ACTING ON SUPEROXIDE AS ACCEPTOR
EC 1.15.1.2 superoxide reductase
*EC 1.17.99.1 4-cresol dehydrogenase (hydroxylating)
EC 1.17.99.2 ethylbenzene hydroxylase
EC 1.18.96.1 superoxide reductase
EC 1.18.96.1 Transferred now EC 1.15.1.2
*EC 1.18. Acting on Iron-Sulfur Proteins as Donors
*EC 1.18.1.1 rubredoxin-NAD+ reductase
*EC 1.18.1.4 rubredoxin-NAD(P)+ reductase
EC 1.18.96 With other, known, acceptors
EC 1.18.96.1 superoxide reductase
EC 1.20. ACTING ON PHOSPHORUS OR ARSENIC IN DONORS
EC 1.20.1 Acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor
EC 1.20.1.1 phosphonate dehydrogenase
EC 1.20.4 Acting on phosphorus or arsenic in donors, with disulfide as acceptor
EC 1.20.4.1 arsenate reductase (glutaredoxin)
EC 1.20.4.2 methylarsonate reductase
EC 1.20.98 Acting on phosphorus or arsenic in donors, with other, known acceptors
EC 1.20.98.1 arsenate reductase (azurin)
EC 1.20.99 Acting on phosphorus or arsenic in donors, with other acceptors
EC 1.20.99.1 arsenate reductase (donor)
EC 1.97.1.5 Transferred now EC 1.20.4.1
EC 1.97.1.6 Transferred now EC 1.20.99.1
EC 1.97.1.7 Transferred now EC 1.20.4.2
EC 1.97.1.8 tetrachloroethene reductive dehalogenase
*EC 2.1.1.41 sterol 24-C-methyltransferase
EC 2.1.1.140 (S)-coclaurine-N-methyltransferase
EC 2.1.1.141 jasmonate O-methyltransferase
EC 2.1.1.142 cycloartenol 24-C-methyltransferase
EC 2.1.1.143 24-methylenesterol C-methyltransferase
*EC 2.1.4.2 scyllo-inosamine-4-phosphate amidinotransferase
*EC 2.3.1.117 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
EC 2.3.1.157 glucosamine-1-phosphate N-acetyltransferase
EC 2.3.1.158 phospholipid:diacylglycerol acyltransferase
*EC 2.4.1.65 3-α-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase
*EC 2.4.1.101 α-1,3-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase
*EC 2.4.1.142 chitobiosyldiphosphodolichol β-mannosyltransferase
*EC 2.4.1.143 α-1,6-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase
*EC 2.4.1.144 β-1,4-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase
*EC 2.4.1.145 α-1,3-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase
*EC 2.4.1.155 α-1,6-mannosyl-glycoprotein 6-β-N-acetylglucosaminyltransferase
*EC 2.4.1.201 α-1,6-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase
*EC 2.4.1.203 trans-zeatin O-β-D-glucosyltransferase
EC 2.4.1.211 1,3-β-galactosyl-N-acetylhexosamine phosphorylase
EC 2.4.1.212 hyaluronan synthase
EC 2.4.1.213 glucosylglycerol-phosphate synthase
EC 2.4.1.214 further modification of proposed entry required before public approval is sought.
EC 2.4.1.215 cis-zeatin O-β-D-glucosyltransferase
EC 2.4.1.216 trehalose 6-phosphate phosphorylase
*EC 2.5.1.2 thiamine pyridinylase
*EC 2.5.1.44 homospermidine synthase
EC 2.5.1.45 homospermidine synthase (spermidine-specific)
EC 2.5.1.46 deoxyhypusine synthase
*EC 2.6.1.37 2-aminoethylphosphonate-pyruvate transaminase
*EC 2.7.1.64 inositol 3-kinase
EC 2.7.1.145 deoxynucleoside kinase
EC 2.7.1.146 ADP-dependent phosphofructokinase
EC 2.7.1.147 ADP-dependent glucokinase
EC 2.7.1.148 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
EC 2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
EC 2.7.8.24 phosphatidylcholine synthase
*EC 2.8.2.8 [heparan sulfate]-glucosamine N-sulfotransferase
EC 2.8.2.12 Deleted entry: heparitin sulfotransferase. Enzyme identical to EC 2.8.2.8, [heparan sulfate]-glucosamine N-sulfotransferase
*EC 2.8.2.23 [heparan sulfate]-glucosamine 3-sulfotransferase 1
EC 2.8.2.29 [heparan sulfate]-glucosamine 3-sulfotransferase 2
EC 2.8.2.30 [heparan sulfate]-glucosamine 3-sulfotransferase 3
EC 2.8.4 Transferring alkylthio groups
EC 2.8.4.1 coenzyme-B sulfoethylthiotransferase
EC 3.1.1.75 poly(3-hydroxybutyrate) depolymerase
EC 3.1.1.76 poly(3-hydroxyoctanoate) depolymerase acyloxyacyl hydrolase
EC 3.1.1.77 acyloxyacyl hydrolase
EC 3.1.3.69 glucosylglycerol 3-phosphatase
EC 3.1.21.7 deoxyribonuclease V
EC 3.1.22.3 Transferred entry: now EC 3.1.21.7, deoxyribonuclease V
*EC 3.2.1 Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds
*EC 3.2.1.4 cellulase
*EC 3.2.1.35 hyalurononglucosaminidase
*EC 3.2.1.70 glucan 1,6-α-glucosidase
EC 3.2.1.90 Deleted, not sufficiently characterised.
*EC 3.2.1.101 mannan endo-1,6-β-mannosidase
EC 3.2.1.145 galactan 1,3-β-galactosidase
EC 3.2.1.146 β-galactofuranosidase
EC 3.2.1.147 thioglucosidase
EC 3.2.1.148 ribosylhomocysteinase
EC 3.2.1.149 β-primeverosidase
EC 3.2.3.1 now EC 3.2.1.147
*EC 3.3.1 Trialkylsulfonium Hydrolases
EC 3.3.1.3 now EC 3.2.1.148
EC 3.3.2.8 limonene-1,2-epoxide hydrolase
EC 3.4.13.21 dipeptidase E
*EC 3.4.14.4 dipeptidyl-peptidase III
*EC 3.4.14.9 tripeptidyl-peptidase I
EC 3.4.21.99 spermosin
EC 3.4.21.100 pseudomonapepsin
EC 3.4.21.101 xanthomonapepsin
EC 3.4.21.102 C-terminal processing peptidase
EC 3.4.22.45 helper-component proteinase
EC 3.4.22.46 L-peptidase
EC 3.4.23.33 Transferred entry: now EC 3.4.21.101, xanthomonapepsin
EC 3.4.23.37 Transferred entry: now EC 3.4.21.100, pseudomonapepsin
EC 3.4.23.43 prepilin peptidase
EC 3.4.23.44 nodavirus endopeptidase
EC 3.4.24.77 snapalysin
EC 3.5.1.87 N-carbamoyl-L-amino-acid hydrolase
EC 3.5.1.88 peptide deformylase
*EC 3.5.2.7 imidazolonepropionase
EC 3.5.2.16 maleimide hydrolase
*EC 3.5.3.8 formimidoylglutamase
*EC 3.6.3.1 Mg2+-ATPase
*EC 3.6.3.2 Mg2+-importing ATPase
*EC 3.6.3.5 Zn2+-exporting ATPase
*EC 3.6.3.7 Na+-exporting ATPase
*EC 3.6.3.8 Ca2+-transporting ATPase
*EC 3.6.3.9 Na+/K+-exchanging ATPase
EC 3.6.3.13 Deleted entry: identical to EC 3.6.3.1
*EC 3.11.1.1 phosphonoacetaldehyde hydrolase
EC 3.13 Acting on Carbon-Sulfur Bonds
EC 3.13.1.1 UDPsulfoquinovose synthase
EC 4.1.1.39 ribulose-bisphosphate carboxylase
EC 4.1.3.37 1-deoxy-D-xylulose 5-phosphate synthase
EC 4.2.1.13 Transferred entry: now EC 4.3.1.17, L-serine ammonia-lyase
EC 4.2.1.14 Transferred entry: now EC 4.3.1.18, D-serine ammonia-lyase
EC 4.2.1.16 Transferred entry: now EC 4.3.1.19, threonine ammonia-lyase
EC 4.2.1.38 Transferred entry: now EC 4.3.1.20, erythro-3-hydroxyaspartate ammonia-lyase
*EC 4.2.1.49urocanate hydratase
*EC 4.2.1.100 cyclohexa-1,5-dienecarbonyl-CoA hydratase
EC 4.2.1.102 now EC 4.2.1.100 cyclohexa-1,5-diene-1-carbonyl-CoA hydratase
EC 4.2.1.103 cyclohexyl-isocyanide hydratase
EC 4.2.1.104 cyanate hydratase
*EC 4.2.2.1 hyaluronate lyase
*EC 4.2.3.12 6-pyruvoyltetrahydropterin synthase
EC 4.2.99.19 2-hydroxypropyl-CoM lyase
*EC 4.3 Carbon-Nitrogen Lyases
EC 4.3.1.16 threo-3-hydroxyaspartate ammonia-lyase
EC 4.3.1.17 L-serine ammonia-lyase
EC 4.3.1.18 D-serine ammonia-lyase
EC 4.3.1.19 threonine ammonia-lyase
EC 4.3.1.20 erythro-3-hydroxyaspartate ammonia-lyase
EC 4.3.99.1 Transferred now EC 4.2.1.104
EC 4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
EC 5.4.2.10 phosphoglucosamine mutase
*EC 5.5.1.4 inositol-phosphate synthase
*EC 6.1.1.13 D-alanine-poly(phosphoribitol) ligase
EC 6.2.1.21 Deleted entry: covered by EC 6.2.1.30, phenylacetate-CoA ligase
EC 6.4.1.6 acetone carboxylase