IUBMB Enzyme Nomenclature

EC 2.7.1.103

Accepted name: viomycin kinase

Reaction: ATP + viomycin = ADP + O-phosphoviomycin

Other name(s): viomycin phosphotransferase; capreomycin phosphotransferase

Systematic name: ATP:viomycin O-phosphotransferase

Comments: Acts also on capreomycins. A serine residue in the peptide antibiotics acts as phosphate-acceptor.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 77000-11-4

References:

1. Skinner, R.H. and Cundliffe, E. Resistance to the antibiotics viomycin and capreomycin in the Streptomyces species which produce them. J. Gen. Microbiol. 120 (1980) 95-104. [PMID: 6163840]

[EC 2.7.1.103 created 1983]


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