IUBMB Enzyme Nomenclature


Accepted name: AMP—thymidine kinase

Reaction: AMP + thymidine = adenosine + dTMP

Glossary: dTMP = thymidine 5'-phosphate

Other name(s): adenylate-nucleoside phosphotransferase;

AMP:dThd kinase; adenylic acid:deoxythymidine 5'-phosphotransferase; AMP:deoxythymidine kinase; AMP:deoxythymidine 5'-phosphotransferase; thymidine phosphotransferase

Systematic name: AMP:thymidine 5'-phosphotransferase

Comments: The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyses this reaction as well as those of EC (thymidine kinase), EC (ADP—thymidine kinase) and EC (dTMP kinase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 60440-28-0


1. Falke, D., Labenz, J., Brauer, D. and Mueller, W.E.G. Adenosine diphosphate: thymidine 5'-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase. Biochim. Biophys. Acta 708 (1982) 99-103. [PMID: 6293576]

2. Falke, D., Nehrbass, W., Brauer, D. and Mueller, W.E.G. Adenylic acid: deoxythymidine 5'-phosphotransferase: evidence for the existence of a novel Herpes simplex virus-induced enzyme. J. Gen. Virol. 53 (1981) 247-255. [PMID: 6267178]

[EC created 1984]

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