IUBMB Enzyme Nomenclature


Accepted name: macrolide 2'-kinase

Reaction: ATP + oleandomycin = ADP + oleandomycin 2'-O-phosphate

Systematic name: ATP:macrolide 2'-O-phosphotransferase

Comments: Erythromycin, spiramycin and some other macrolide antibiotics can also act as acceptors.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 116036-69-2


1. O'Hara, K., Kanda, T. and Kono, M. Structure of a phosphorylated derivative of oleandomycin, obtained by reaction of oleandomycin with an extract of an erythromycin-resistant strain of Escherichia coli. J. Antibiot. 41 (1988) 823-827. [PMID: 3042731]

[EC created 1992]

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