IUBMB Enzyme Nomenclature


Accepted name: inositol-tetrakisphosphate 5-kinase

Reaction: ATP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate

Other name(s): 1D-myo-inositol-tetrakisphosphate 5-kinase

Systematic name: ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase

Comments: The enzyme from plants and yeast can also use Ins(1,2,3,4,6)P5 as a substrate [2].

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 123940-40-9


1. Shears, S.B. The pathway of myo-inositol 1,3,4-trisphosphate phosphorylation in liver. Identification of myo-inositol 1,3,4-trisphosphate 6-kinase, myo-inositol 1,3,4-trisphosphate 5-kinase, and myo-inositol 1,3,4,6-tetrakisphosphate 5-kinase. J. Biol. Chem. 264 (1989) 19879-19886. [PMID: 2584198]

2. Stevenson-Paulik, J., Odom, A.R. and York, J.D. Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases. J. Biol. Chem. 277 (2002) 42711-42718. [PMID: 12226109]

[EC created 1992]

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