IUBMB Enzyme Nomenclature


Accepted name: ADP-specific phosphofructokinase

Reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate

For diagram of reaction click here.

Other name(s): ADP-6-phosphofructokinase; ADP-dependent phosphofructokinase

Systematic name: ADP:D-fructose-6-phosphate 1-phosphotransferase

Comments: ADP can be replaced by GDP, ATP and GTP, to a limited extent. Divalent cations are necessary for activity, with Mg2+ followed by Co2+ being the most effective.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 237739-62-7


1. Tuininga, J.E., Verhees, C.H., van der Oost, J., Kengen, S.W., Stams, A.J. and de Vos, W.M. Molecular and biochemical characterization of the ADP-dependent phosphofructokinase from the hyperthermophilic archaeon Pyrococcus furiosus. J. Biol. Chem. 274 (1999) 21023-21028. [PMID: 10409652]

[EC created 2001]

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