IUBMB Enzyme Nomenclature


Accepted name: L-threonine kinase

Reaction: ATP + L-threonine = ADP + O-phospho-L-threonine

For diagram of reaction click here.

Other name(s): PduX

Systematic name: ATP:L-threonine O3-phosphotransferase

Comments: The enzyme is involved in the de novo synthesis of adenosylcobalamin. It is specific for ATP and free L-threonine. In the bacterium Salmonella enterica the activity with CTP, GTP, or UTP is 6, 11, and 3% of the activity with ATP.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Fan, C. and Bobik, T.A. The PduX enzyme of Salmonella enterica is an L-threonine kinase used for coenzyme B12 synthesis. J. Biol. Chem. 283 (2008) 11322-11329. [PMID: 18308727]

2. Fan, C., Fromm, H.J. and Bobik, T.A. Kinetic and functional analysis of L-threonine kinase, the PduX enzyme of Salmonella enterica. J. Biol. Chem. 284 (2009) 20240-20248. [PMID: 19509296]

[EC created 2012]

Return to EC 2.7.1 home page
Return to EC 2.7 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page