IUBMB Enzyme Nomenclature

EC 2.7.1.224

Accepted name: cytidine diphosphoramidate kinase

Reaction: ATP + cytidine 5'-diphosphoramidate = ADP + cytidine 3'-phospho-5'-diphosphoramidate

Systematic name: ATP:cytidine 5'-diphosphoramidate 3'-phosphotransferase

Comments: The enzyme, characterized from the bacterium Campylobacter jejuni, is involved in formation of a unique O-methyl phosphoramidate modification on specific sugar residues within the bacterium's capsular polysaccharides.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Taylor, Z.W. and Raushel, F.M. Cytidine diphosphoramidate kinase: an enzyme required for the biosynthesis of the O-methyl phosphoramidate modification in the capsular polysaccharides of Campylobacter jejuni. Biochemistry 57 (2018) 2238-2244. [PMID: 29578334]

[EC 2.7.1.224 created 2018]


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