Reaction: 1-phosphatidyl-1D-myo-inositol + a very-long-chain (2'R)-2'-hydroxy-phytocermide = 1,2-diacyl-sn-glycerol + a very-long-chain inositol phospho-(2'R)-2'-hydroxyphytoceramide
Glossary: a very-long-chain inositol phospho-(2'R)-2'-hydroxyphytoceramide = a very-long-chain inositol phospho-α-hydroxyphytoceramide = IPC
Other name(s): AUR1 (gene name); KEI1 (gene name)
Systematic name: 1-phosphatidyl-1D-myo-inositol:(2'R)-2'-hydroxy-phytoceramide phosphoinositoltransferase
Comments: The enzyme, characterized from yeast, attaches a phosphoinositol headgroup to α-hydroxyphytoceramides, generating a very-long-chain inositol phospho-α hydroxyphytoceramide (IPC), the simplest of the three complex sphingolipids produced by yeast.
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