IUBMB Enzyme Nomenclature


Accepted name: hydroxymethylpyrimidine kinase

Reaction: ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine = ADP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

Other name(s): hydroxymethylpyrimidine kinase (phosphorylating)

Systematic name: ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase

Comments: CTP, UTP and GTP can act as donors.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9026-55-5


1. Lewin, L.M. and Brown, G.M. The biosynthesis of thiamine. III. Mechanism of enzymatic formation of the pyrophosphate ester of 2-methyl-4-amino-5-hydroxymethylpyrimidine. J. Biol. Chem. 236 (1961) 2768-2771.

[EC created 1965]

Return to EC 2.7.1 home page
Return to EC 2.7 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page