Reaction: ATP + 4-methyl-5-(2-hydroxyethyl)thiazole = ADP + 4-methyl-5-(2-phosphooxyethyl)thiazole
Other name(s): hydroxyethylthiazole kinase (phosphorylating); 4-methyl-5-(β-hydroxyethyl)thiazole kinase
Systematic name: ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9026-56-6
References:
1. Lewin, L.M. and Brown, G.M. The biosynthesis of thiamine. III. Mechanism of enzymatic formation of the pyrophosphate ester of 2-methyl-4-amino-5-hydroxymethylpyrimidine. J. Biol. Chem. 236 (1961) 2768-2771.