IUBMB Enzyme Nomenclature


Accepted name: NADH kinase

Reaction: ATP + NADH = ADP + NADPH

Other name(s): reduced nicotinamide adenine dinucleotide kinase (phosphorylating); DPNH kinase; reduced diphosphopyridine nucleotide kinase; NADH2 kinase

Systematic name: ATP:NADH 2'-phosphotransferase

Comments: CTP, ITP, UTP and GTP can also act as phosphate donors (in decreasing order of activity). The enzyme is specific for NADH. Activated by acetate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 62213-39-2


1. Griffiths, M.M. and Bernofsky, C. Purification and properties of reduced diphosphopyridine nucleotide kinase from yeast mitochondria. J. Biol. Chem. 247 (1972) 1473-1478. [PMID: 4335000]

[EC created 1976 (EC created 1978, incorporated 1978)]

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