IUBMB Enzyme Nomenclature


Accepted name: creatine kinase

Reaction: ATP + creatine = ADP + phosphocreatine

For diagram of reaction click here.

Other names: ATP:creatine phosphotransferase; CK; MM-CK; MB-CK; BB-CK; creatine phosphokinase; creatine phosphotransferase; phosphocreatine kinase; adenosine triphosphate-creatine transphosphorylase; Mi-CK; CK-BB; CK-MM; CK-MB; CKMiMi; MiMi-CK

Systematic name: ATP:creatine N-phosphotransferase

Comments: N-Ethylglycocyamine can also act as acceptor.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9001-15-4


1. Ennor, A.H., Rosenberg, H. and Armstrong, M.D. Specificity of creatine phosphokinase. Nature 175 (1955) 120 only.

2. Keutel, H.J., Jacobs, H.K., Okabe, K., Yue, R.H. and Kuby, S.A. Studies on adenosine triphosphate transphosphorylases. VII. Isolation of the crystalline adenosine triphosphate-creatine transphosphorylase from calf brain. Biochemistry 7 (1968) 4283-4290. [PMID: 5750168]

3. Kuby, S.A., Noda, L. and Lardy, H.A. Adenosine triphosphate-creatine transphosphorylase. I. Isolation of the crystalline enzyme from rabbit muscle. J. Biol. Chem. 209 (1954) 191-201.

4. Kuby, S.A. and Noltmann, E.A. ATP-creatine transphosphorylase, in Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd edn., vol. 6, Academic Press, New York, 1962, pp. 515-603.

[EC created 1961]

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