Biosythesis of Brucine and Related Alkaloids

Reactions based on Hong, B., Grzech, D., Caputi, L., Sonawane, P., Lopez, C.ER., Kamileen, M.O., Hernandez Lozada, N.J., Grabe, V. and O'Connor, S.E. Biosynthesis of strychnine. Nature 607 (2022) 617-622. [PMID: 35794473]

© IUBMB 2024

Return to:
enzymes homepage
brucine biosynthesis
EC 1.14.14.189 strychnine 10-hydroxylase
EC 1.14.14.190 β-colubrine 11-hydroxylase
EC 2.1.1.397 hydroxystrychnine O-methyltransferase