Inositol Catabolism

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© IUBMB 2014

For numbering of atoms in inositol see cyclitol nomenclature. It is now normal to use 1D-numbering for myo-inositol.

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myo-inositol biosynthesis
EC 1.1.1.18 inositol 2-dehydrogenase
EC 1.1.1.369 D-chiro-inositol 1-dehydrogenase
EC 1.1.1.370 scyllo-inositol 2-dehydrogenase (NAD+)
EC 1.1.1.371 scyllo-inositol 2-dehydrogenase (NADP+)
EC 1.2.1.27 methylmalonate-semialdehyde dehydrogenase (acylating)
EC 2.7.1.92 5-dehydro-2-deoxygluconokinase
EC 3.7.1.22 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing)
EC 4.1.2.29 5-dehydro-2-deoxyphosphogluconate aldolase
EC 4.2.1.44 myo-inosose-2 dehydratase
EC 5.3.1.30 5-deoxy-glucuronate isomerase
EC 5.3.99.11 2-keto-myo-inositol isomerase