Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB)

Enzyme Nomenclature

Supplement 11 (2005)

The following documents with additions and amendments to Enzyme Nomenclature have been approved after public review:

New enzymes (February 2005, approved April 2005)
New enzymes (February 2005, approved May 2005)
New enzymes (July 2005, approved September 2005)
New enzymes (September 2005, approved November 2005)
New bile acid enzymes (September 2005, approved November 2005)
New protein kinase enzymes (December 2005, approved February 2006)
Minor changes
An asterisk before 'EC' indicates that this is an amendment to an existing enzyme rather than a new enzyme entry.


*EC glycerol-3-phosphate dehydrogenase (NAD+)
*EC methylglyoxal reductase (NADH-dependent)
*EC glycerol-3-phosphate dehydrogenase [NAD(P)+]
EC methylglyoxal reductase (NADPH-dependent)
EC S-(hydroxymethyl)glutathione dehydrogenase
EC 3"-deamino-3"-oxonicotianamine reductase
EC isocitrate—homoisocitrate dehydrogenase
EC D-arabinitol dehydrogenase (NADP+)
EC xanthoxin dehydrogenase
EC now included with EC
EC deleted entry replaced by EC and EC
EC abscisic aldehyde oxidase
EC deleted, identical to EC
*EC δ4-3-oxosteroid 5β-reductase
EC Deleted now EC
*EC arogenate dehydrogenase
*EC 1,2-dihydroxy-3-methyl-1,2-dihydrobenzoate dehydrogenase
EC arogenate dehydrogenase (NADP+)
EC arogenate dehydrogenase [NAD(P)+]
EC now EC
*EC 2-oxoglutarate synthase
EC pyrroloquinoline-quinone synthase
EC all-trans-retinol 13,14-reductase
EC aspartate dehydrogenase
*EC methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.5.7 With an iron-sulfur protein as acceptor
EC methylenetetrahydrofolate reductase (ferredoxin)
EC NAD(P)H dehydrogenase (quinone)
EC now EC
*EC urate oxidase
EC deleted entry now included with EC
*EC CoA-disulfide reductase
EC sulfiredoxin
EC ribosyldihydronicotinamide dehydrogenase (quinone)
EC violaxanthin de-epoxidase
EC 9-cis-epoxycarotenoid dioxygenase
EC deacetoxycephalosporin-C hydroxylase
*EC deacetoxyvindoline 4-hydroxylase
EC 2'-deoxymugineic-acid 2'-dioxygenase
EC mugineic-acid 3-dioxygenase
EC 3-phenylpropionate dioxygenase
*EC cholestanetriol 26-monooxygenase
*EC 4'-methoxyisoflavone 2'-hydroxylase
EC isoflavone 2'-hydroxylase
EC zeaxanthin epoxidase
EC deoxysarpagine hydroxylase
EC phenylacetone monooxygenase
EC (+)-abscisic acid 8'-hydroxylase
EC lithocholate 6β-hydroxylase
EC 7α-hydroxycholest-4-en-3-one 12α-hydroxylase
EC 5β-cholestane-3α,7α-diol 12α-hydroxylase
EC taurochenodeoxycholate 6α-hydroxylase
EC cholesterol 24-hydroxylase
EC 24-hydroxycholesterol 7α-hydroxylase
EC 25-hydroxycholesterol 7α-hydroxylase
EC lathosterol oxidase
EC cholesterol 25-hydroxylase
*EC CDP-4-dehydro-6-deoxyglucose reductase
EC bile-acid 7α-dehydroxylase
EC 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA 24-hydroxylase
*EC nitrogenase
*EC tRNA guanosine-2'-O-methyltransferase
*EC tabersonine 16-O-methyltransferase
*EC 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase
*EC sterigmatocystin 8-O-methyltransferase
EC glycine/sarcosine N-methyltransferase
EC sarcosine/dimethylglycine N-methyltransferase
EC N-acetylornithine carbamoyltransferase
*EC bile acid-CoA:amino acid N-acyltransferase
*EC aralkylamine N-acetyltransferase
*EC deacetylvindoline O-acetyltransferase
EC 3-oxoadipyl-CoA thiolase
EC deacetylcephalosporin-C acetyltransferase
EC propanoyl-CoA C-acyltransferase
*EC monogalactosyldiacylglycerol synthase
EC deleted entry
*EC galactolipid galactosyltransferase
EC deleted now EC
EC digalactosyldiacylglycerol synthase
EC NDP-glucose—starch glucosyltransferase
*EC squalene synthase
*EC phytoene synthase
*EC D-amino acid transaminase
EC aspartate—prephenate aminotransferase
EC glutamate—prephenate aminotransferase
EC nicotianamine aminotransferase
EC now divided into EC, EC, EC, EC, EC, EC, EC, EC, EC, EC, EC, EC and EC
EC now EC
EC now EC
EC now EC
EC now EC
EC now EC
EC now EC and EC
EC now EC
EC now EC
EC now EC
EC now part of EC
EC now part of EC
EC now EC
EC now EC
EC now EC
EC now EC
EC now EC
EC now EC
EC now EC
EC now EC
EC now EC
EC N-acetylgalactosamine kinase
EC propionate kinase
EC now EC
EC now EC
EC phosphoglucan, water dikinase
EC 2.7.10 Protein-tyrosine kinases
EC receptor protein-tyrosine kinase
EC non-specific protein-tyrosine kinase
EC 2.7.11 Protein-serine/threonine kinases
EC non-specific serine/threonine protein kinase
EC [pyruvate dehydrogenase (acetyl-transferring)] kinase
EC dephospho-[reductase kinase] kinase
EC [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase
EC [isocitrate dehydrogenase (NADP+)] kinase
EC [tyrosine 3-monooxygenase] kinase
EC myosin-heavy-chain kinase
EC Fas-activated serine/threonine kinase
EC Goodpasture-antigen-binding protein kinase
EC IκB kinase
EC cAMP-dependent protein kinase
EC cGMP-dependent protein kinase
EC protein kinase C
EC rhodopsin kinase
EC β-adrenergic-receptor kinase
EC G-protein-coupled receptor kinase
EC Ca2+/calmodulin-dependent protein kinase
EC myosin-light-chain kinase
EC phosphorylase kinase
EC elongation factor 2 kinase
EC polo kinase
EC cyclin-dependent kinase
EC [RNA-polymerase]-subunit kinase
EC mitogen-activated protein kinase
EC mitogen-activated protein kinase kinase kinase
EC tau-protein kinase
EC [acetyl-CoA carboxylase] kinase
EC tropomyosin kinase
EC low-density-lipoprotein receptor kinase
EC receptor protein serine/threonine kinase
EC [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
EC 2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
EC dual-specificity kinase
EC mitogen-activated protein kinase kinase
EC 2.7.13 Protein-histidine kinases
EC protein-histidine pros-kinase
EC protein-histidine tele-kinase
EC histidine kinase
EC 2.7.99 Other protein kinases
EC triphosphate—protein phosphotransferase
*EC bile-salt sulfotransferase
EC scymnol sulfotransferase
EC N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase
EC glycochenodeoxycholate sulfotransferase
*EC poly(3-hydroxyoctanoate) depolymerase
EC transferred entry now EC
EC bile-acid-CoA hydrolase
EC choloyl-CoA hydrolase
EC mannosylglycoprotein endo-β-mannosidase
EC fructan β-(2,1)-fructosidase
EC fructan β-(2,6)-fructosidase
EC oligosaccharide reducing-end xylanase
EC mannan-binding lectin-associated serine protease-2
EC rhomboid protease
*EC acetylspermidine deacetylase
EC N-substituted formamide deformylase
EC pantetheine hydrolase
EC glutaryl-7-aminocephalosporanic-acid acylase
EC deleted probably EC
EC 2'-hydroxybiphenyl-2-sulfinate desulfinase
EC phosphonopyruvate decarboxylase
EC 4-hydroxyphenylacetate decarboxylase
EC D-dopachrome decarboxylase
EC 3-dehydro-L-gulonate-6-phosphate decarboxylase
*EC arogenate dehydratase
EC bile-acid 7α-dehydratase
EC 3α,7α,12αtrihydroxy-5β-cholest-24-enoyl-CoA dehydratase
EC chondroitin B lyase
EC transferred entry now EC
EC S-(hydroxymethyl)glutathione synthase
EC 2-hydroxypropyl-CoM lyase
EC phenylacetaldoxime dehydratase
*EC L-ribulose-5-phosphate 4-epimerase
*EC CDP-paratose 2-epimerase
EC L-ribulose-5-phosphate 3-epimerase
EC deleted entry
*EC L-dopachrome isomerase
EC capsanthin/capsorubin synthase
EC neoxanthin synthase
*EC cholate—CoA ligase
EC deleted now EC
EC glutamate—putrescine ligase
*EC dihydrofolate synthase
*EC tetrahydrofolate synthase

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