IUBMB Enzyme Nomenclature


Accepted name: mevalonate-3-phosphate 5-kinase

Reaction: ATP + (R)-3-phosphomevalonate = ADP + 3,5-bisphosphomevalonate

For diagram of reaction click here.

Systematic name: ATP:(R)-3-phosphomevalonate 5-phosphotransferase

Comments: Mevalonate 3-kinase (EC and mevalonate-3-phosphate-5-kinase act sequentially in an alternate mevalonate pathway in the archaeon Thermoplasma acidophilum.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Vinokur, J.M., Korman, T.P., Cao, Z. and Bowie, J.U. Evidence of a novel mevalonate pathway in archaea. Biochemistry 53 (2014) 4161-4168. [PMID: 24914732]

[EC created 2014]

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